Abstract

Heavy-ion beams at 106 particles per second have been applied to the treatment of deep-seated inoperable tumors in the therapy terminal of the Heavy Ion Research Facility in Lanzhou (HIRFL) which is located at the Institute of Modern Physics, Chinese Academy of Sciences (IMP, CAS). An accurate low current measurement circuit following a Faraday cup was developed to monitor the beam current at pA range. The circuit consisted of a picoammeter with a bandwidth of 1kHz and a gated integrator (GI). A low input bias current precision amplifier and new guarding and shielding techniques were used in the picoammeter circuit which allowed as to measure current less than 1pA with a current gain of 0.22V/pA and noise less than 10fA. This paper will also describe a novel compensation approach which reduced the charge injection from switches in the GI to 10−18C, and a T-switch configuration which was used to eliminate leakage current in the reset switch.

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