Abstract
The malignant growth of Guerin's carcinoma was shown to induce increase of aminotransferases' enzymatic activities. It was established that introduction of the antioxidant substance "GRIN" led to normalization of aminotransferases' activities in blood serum and also had essential inhibitory effect on the tumor growth.
Highlights
There are nearly 6 million new registered cases of malignant disease all over the world
Guerin's carcinoma (GC) is a strain of modified cancer derived from the rat spontaneous adenocarcinoma
We found out that studied substance stabilized growth of GC
Summary
There are nearly 6 million new registered cases of malignant disease all over the world. Uterine cancer (adenocarcinoma) is a widespread disease among women ranking 4th place after breast, skin, and gastrointestinal cancers. The rate of uterine cancer incidence increases steadily. In Ukraine, this value is 26.4 per 100,000 population. Women are starting to get sick at the age of 40-54 years old, the peak of the disease occurs at the age of 60-64 years [1,2]. At the present time Guerin's carcinoma (GC) is known to be an optimal model of this pathology for research. GC is a strain of modified cancer derived from the rat spontaneous adenocarcinoma
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