Abstract

Ameliorative Effect of Thymus Oil on Paracetamol Induced Hepato-Renal Toxicity: A Biochemical, Antioxidant and Histopathological Studies

Highlights

  • The use of plants in medicine is an age-long practice in various parts of the globe for both preventive and curative

  • In this study we evaluated the level of protection of thymus oil against the hepato-renal toxicity of paracetamol in rats

  • The level of AST, ALT and total bilirubin increased significantly in paracetamol treated rats (Group II), while the content of albumin decreased significantly when compared with control (Group I)

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Summary

Introduction

The use of plants in medicine is an age-long practice in various parts of the globe for both preventive and curative. It is estimated that about 80% of the world population relies on botanical preparations as medicine to meet their health [1]. Liver diseases are considered as a major public health problem around the world due to their potentiality to cause morbidity and mortality [2]. About more than two million people in the world die annually from liver-related disorders [3]. The general functions of the kidneys are to regulate blood pressure, acid-base balance, electrolyte balance and extracellular fluid volume. They eliminate substances from the body including metabolic products, various toxins and other foreign substances such as drugs, pesticides and food additives [4]

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