Abstract
Summary Robust pre-contrast reference T1 values using ShMOLLI in 231 normal human controls aged 11 to 81 years demonstrate little dependence on gender, age or heart rates. Background Quantitative T1-mapping is rapidly becoming a clinical Cardiovascular Magnetic Resonance (CMR) imaging tool that can distinguish normal from diseased myocardium. The usefulness of any quantitative measurement to identify disease lies in its ability to detect significant differences from an established normal range of values. In this study we aim to establish a large database for the normal range of T1 values in healthy human myocardium and to examine any differences based on age and gender.
Highlights
Quantitative T1-mapping is rapidly becoming a clinical Cardiovascular Magnetic Resonance (CMR) imaging tool that can distinguish normal from diseased myocardium
In this study we aim to establish a large database for the normal range of T1 values in healthy human myocardium and to examine any differences based on age and gender
All data were acquired in 1.5T MR systems (Siemens, Avanto) using the ShMOLLI sequence for T1 maps as previously described [Piechnik at al
Summary
In this study we aim to establish a large database for the normal range of T1 values in healthy human myocardium and to examine any differences based on age and gender
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