Abstract
Rotavirus is the leading cause of acute gastroenteritis in children, and vaccines are the most effective measure to control rotavirus diarrhea. Currently, two vaccines, namely Rotarix and RotaTeq, are widely used worldwide. In addition, several vaccines are licensed in some countries. This review summarized the effectiveness of licensed rotavirus vaccines and the potential factors which might affect the effectiveness of these vaccines. In addition, progress in novel vaccine candidates in development was also included in this review. Key words: Rotavirus; Vaccine; Effectiveness
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