Acute Respiratory Infection by Chlamydophila pneumoniae and Mycoplasma pneumoniae in a Population of Older Adults in Colombia

Nidi Lorena Corredor Cubides,Laura Bettin Torres,Lilia Patricia Guiza Forero,Jeanette Coriat Budik,Maria Fernanda Gutiérrez Fernández,Pilar Rocio Vargas Chacón,Juan Camilo Segura Salgero,Hugo Diez Ortega,Maria Juliana Silva Valencia,Marylin Hidalgo Díaz,Karent Juileth Beltrán Suárez

doi:10.11144/javeriana.umed58-4.pneu

Nidi Lorena Corredor Cubides, Laura Bettin Torres + Show 9 more

Open Access

https://doi.org/10.11144/javeriana.umed58-4.pneu

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Journal: Universitas Medica	Publication Date: Oct 19, 2017
License type: CC BY 4.0

Affiliation: Pontificia Universidad Javeriana

Abstract

AbstractIntroduction: Acute Respiratory Infection (ARI) is a heterogeneous group of viral and bacterial respiratory pathologies including Chlamydophila pneumoniae (CP) and Mycoplasma pneumoniae (MP) that are not routinely identified; these infections in the older adults have mortality rates 3 to 5 times higher than that recorded in other age groups. Methods: this study was conducted prospectively to determine the proportion of atypical bacterial pathogens in older adults with ARI in Bogotá. Microbiological diagnosis was determined by real-time PCR (qPCR) in samples of respiratory origin and serology for antibodies IgG, IgA and IgM to MP and CP. Results: A total of 71 patients were enrolled from 2012 to 2013. Upper respiratory infections were diagnosed in the 69% of patients and lower respiratory infections in 31%. MP was identified in 9.8% and CP in 8.5%. Conclusions: these findings indicated that CP and MP must be viewed as a significant etiological agent of ARI in older adults in Bogotá.

Highlights

Acute Respiratory Infection (ARI) is a heterogeneous group of viral and bacterial respiratory pathologies including Chlamydophila pneumoniae (CP) and Mycoplasma pneumoniae (MP) that are not routinely identified; these infections in the older adults have mortality rates 3 to 5 times higher than that recorded in other age groups
Conclusions: these findings indicated that CP and MP must be viewed as a significant etiological agent of ARI in older adults in Bogotá
The ARI includes upper respiratory tract infections (URTI) and lower respiratory tract infections (LRTI), a term that includes a number of inflammatory pathologies called according to the affected site such as rhinosinusitis, otitis, mastoiditis, pharyngitis, tonsillitis, bronchitis, pneumonia, common cold, among others [1,2,3]

Summary

Introduction

Acute Respiratory Infection (ARI) is a heterogeneous group of viral and bacterial respiratory pathologies including Chlamydophila pneumoniae (CP) and Mycoplasma pneumoniae (MP) that are not routinely identified; these infections in the older adults have mortality rates 3 to 5 times higher than that recorded in other age groups. Methods: this study was conducted prospectively to determine the proportion of atypical bacterial pathogens in older adults with ARI in Bogotá. The ARI includes upper respiratory tract infections (URTI) and lower respiratory tract infections (LRTI), a term that includes a number of inflammatory pathologies called according to the affected site such as rhinosinusitis, otitis, mastoiditis, pharyngitis, tonsillitis, bronchitis, pneumonia, common cold, among others [1,2,3]. The prevalence of this disease is higher in children under 5 years, people with some chronic underlying disease, immunosuppression and people over 60 years old [5]

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Conclusion