Acute forms of pemphigus.

Abstract

IN A DISCUSSION of acute pemphigus we must be careful to distinguish between the rare form designated as acute febrile grave pemphigus (so-called pemphigus acutus) and the acute forms or phases of pemphigus vulgaris. It is the latter condition with which we are chiefly concerned here, but the former will be discussed briefly. ACUTE FEBRILE GRAVE PEMPHIGUS Acute febrile grave pemphigus is characterized by a peracute bullous eruption, accompanied by marked symptoms of a severe septic state, and a fatal termination. The onset is sudden and the eruption extensive, beginning as large bullae that often become hemorrhagic. The bullae grow rapidly and soon burst, leaving large, moist or bloody denuded areas that become confluent, resembling in appearance an extensive burn. A high septic fever, chills, and often diarrhea accompany the cutaneous eruption. The patient's course is rapidly downhill, and death ensues in one to three weeks. The condition