Abstract
Aim. To evaluate and compare the accuracy of determining volemic status by remote dielectric sensing (ReDS) with computed tomography (CT) in patients with acute decompensated heart failure (ADHF).Materials and methods. In 33 patients with chronic heart failure (CHF) hospitalized in the hospital due to acute decompensation of heart failure, twice during hospitalization (on the day of admission and on the day of discharge from the hospital) the determination of the volemic status was performed using ReDS, chest computed tomography (CCT) and chest X-ray. ReDS measurement was compared with CT data using software that allows the use of semi-automated tools to determine mean lung tissue density (MLD). MLD results from Hounsfield units [HU] were converted to fluid levels (HU %), which allowed comparison with ReDS values. In addition, to assess the effect of physical activity on the dynamics of pulmonary congestion, a 6-minute walk test (6MWT) were performed with subsequent determination of the volemic status by the ReDS method.Results. A medium correlation was found between CCT and ReDS data (r = +6.0, p = 0.0002). In the dynamics statistically significant decrease of hypervolemia according to CCT data, which was reflected in the decrease of ReDS index. The fluid content in lungs according to ReDS on average at admission amounted to 37.1 ± 5.3%, at discharge 34.2 ± 4.1% (p = 0.0155). MLD according to CCT at admission was 26.5 ± 6.4 at discharge 22.7 ± 5.6 (P<0.0001). At the same time positive dynamics of NT-proBNP concentration was determined, which decreased by 45.6% (p = 0.0069). Differences in ReDS before and after physical activity 6MWT was revealed – 35.2 ± 4.2% in comparison with the initial index 34.2 ± 4.1% (p = 0.0001). A strong correlation was found between the ReDS score before and after 6MWT at discharge (r = +0.7, p = 0.0001)
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