Abnormal villous morphology in abortus specimens is not increased in ART pregnancies

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Increased incidences of placenta previa, abnormal cord insertion and abruption have been described following ART. Anecdotal experience suggests that abnormal villous morphology (AVM) is diagnosed more frequently in abortuses following ART. AVM specimens have a partial mole-like morphology and equivalent staining, but do not share the fully developed features of a partial mole. Further, AVM seems more frequent in aneuploid pregnancies. The objectives of this study were to determine the prevalence of AVM in ART pregnancies compared to non-ART pregnancies, and the ability of AVM to predict chromosomal abnormalities.