VP44.13: Prenatal ultrasound diagnosis of abnormal placental cord insertion and pregnancy outcome

Abstract

Abnormal placental cord insertion includes marginal and velamentous placental cord insertion. With the development of obstetric ultrasound, such abnormal placental cord insertion can be diagnosed prenatal, and the relationship between the abnormal placental cord insertion of prenatal diagnosis and the pregnancy outcome is to be investigated. We performed a prospective study of singleton and multiple pregnancies women undergoing obstetric ultrasonography between 20–24 weeks of gestation at Ewha Women's University Hospital from February 2019 to October 2020. For the characteristics of pregnant women and pregnancy outcome, continuous variables were expressed as mean ± standard deviation and were compared using Student's t-test, or median (IQR) using Mann-Whitney test. Abnormal placental cord insertion was confirmed in 23 cases (6.42%) after a total of 358 deliveries, which 18 cases (5.02%) of marginal cord insertion were found, and 5 cases (1.40%) of velamentous placental cord insertion. Preterm birth, pre-eclampsia, fetal anomaly, postpartum hemorrhage, SGA, and LBW were significantly increased. (P-value< 0.05). Delivery by primary Caesarean section, gestational diabetes mellitus, low APGAR score was not statistically significant, but showed a tendency to increase. The results are given in table 1. Abnormal placental cord insertion is associated with poor pregnancy outcomes. Detecting abnormalities in the placenta attachment area before delivery can improve the prognosis of pregnancy. More cohort study is needed to evaluate the effects of abnormal placental cord insertion and pregnancy outcome. VP44.13: Table 1. Association of abnormal placental cord insertion with pregnancy outcome Central cord insertion (n = 335) Abnormal cord insertion (n = 23)