Abstract

Solitary Fibrous Tumor of the Pleura (SFTP) is an exceptionally rare mesenchymal tumor that typically originates from the visceral pleura and constitutes less than 5% of all pleural tumors. While it often displays benign histological features, the tumor’s behavior remains enigmatic and less comprehensively understood, primarily owing to its limited incidence and case studies. We present two cases of SFTP. The First one was a small pleural nodule a nodule in a 61 year old patien, confirmed as a SFTP through CT-guided biopsy. Successful tumor resection was performed, with histopathological confirmation, and the patient remained recurrence-free for two years. The second one was incidental finding in a 68-year-old patient of a huge pleural mass with necrotic regions and microcalcifications on imaging. Surgical removal revealed an encapsulated tumor with myxoid features, classified as an intermediate-risk SFTP. The patient experienced no complications and had no local recurrence 16 months post-surgery. Solitary fibrous tumors within the pleura are uncommon. The preferred treatment approach is surgical resection, with diligent post-operative monitoring.

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