Abstract
ObjectivesTo compare the effects of a stannous fluoride dentifrice and a sodium fluoride dentifrice on dentinal hypersensitivity when used with an oxalate-based regimen combining in-office and at-home treatment.Materials and methodsIn this single-center, randomized, controlled, double-blind, pilot clinical trial, 30 subjects were professionally treated at baseline with a 3% oxalate/potassium salt solution on up to two target teeth, then randomized 1:1 to either 0.454% stannous fluoride or 0.243% sodium fluoride overlabeled dentifrice. Both groups were given 6 sensitivity strips (3.14% potassium oxalate gel) and a soft, manual toothbrush. Subjects were permitted to apply strips on up to two teeth, up to three times per tooth, at home as desired throughout the study. Dentinal sensitivity (cold air blast challenge) was assessed at baseline, immediately after post-professional treatment, and at day 60 using the Schiff scale and a Visual Analog Scale (VAS).ResultsImmediately after professional oxalate treatment, the overall mean Schiff and VAS score decreased 25.6% and 22.4% from baseline, respectively (p ≤ 0.001 for both). At day 60, further reductions in both mean scores were seen in both groups. There were no significant differences between the groups at day 60. All treatments were well tolerated.ConclusionsIn subjects treated with oxalates for dentinal hypersensitivity, both stannous fluoride and sodium fluoride dentifrices are well tolerated, are feasible for routine use, and do not detract from the desensitizing effects of an in-office and at-home oxalate combination treatment regimen.Clinical relevanceEither stannous fluoride or sodium fluoride dentifrices can be recommended to dentinal hypersensitivity patients who undergo professional oxalate treatment.
Highlights
Dentinal hypersensitivity, characterized by short, sharp pain from exposed dentin in response to thermal, evaporative, tactile, osmotic, or chemical stimuli [1], is a widespread clinical problem [2, 3]
Pain arises from altered fluid flow in dentinal tubules in response to temperature, desiccation, or osmotic balance fluctuations, resulting in nociceptor activation in the pulp/dentin border area [4]
One randomized, controlled study examined the efficacy of a daily potassium oxalate mouthrinse versus a placebo mouthrinse for dentinal hypersensitivity and found significantly greater improvements at week 4 in the experimental group than in the placebo group [16]
Summary
Dentinal hypersensitivity, characterized by short, sharp pain from exposed dentin in response to thermal, evaporative, tactile, osmotic, or chemical stimuli [1], is a widespread clinical problem [2, 3]. Pain arises from altered fluid flow in dentinal tubules in response to temperature, desiccation, or osmotic balance fluctuations, resulting in nociceptor activation in the pulp/dentin border area [4]. One randomized, controlled study examined the efficacy of a daily potassium oxalate mouthrinse versus a placebo mouthrinse for dentinal hypersensitivity and found significantly greater improvements at week 4 in the experimental group than in the placebo group [16]. A second placebo-controlled study compared the efficacy of professionally applied versus patient-applied dipotassium oxalate monohydrate dental strips at 30 min, week 4, and week 8 [17]. Both types of strip application produced significant improvements in dentinal hypersensitivity at all time points
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
