A Radiological Encomium Depicting Pancreatic Fibrosis and Sarcopenia: A Research Perspective

Abstract

Aims and Objectives: In this study we compared DW MRI findings with the results of histological examination and CT findings in patients with chronic pancreatitis and pancreatic cancer, to confirm a non-invasive diagnostic method, determining pancreatic fibrosis. Moreover, we looked for correlation between histologically determined PF and sarcopenia, since this pathology is highly suspected in patients of our research.Materials and Methods: We collected a group of 9 patients, who underwent surgical resection of the pancreas due to pancreatic cancer or chronic pancreatitis. All patients were treated at the Department of Gastroenterology and Surgery of P.B.M hospital, Bikaner, Rajasthan after being approved by the ethical committee of the assocaited Sardar Patel Medical College, Bikaner. All examinations and surgeries were performed in 2017.Conclusion: We found that ADC value in histologically determined fibrotic pancreatic tissue is significant lower. Since DW MRI can be performed relatively quickly, does not require administration of gadolinium-based contrast agents and enables qualitative and quantitative assessment of tissue diffusivity, it can be routinely implemented in clinical protocols.