A modern view of the pathogenesis of osteoarthritis and the choice of effective symptomatic slow action anti-inflammatory drugs in terms of recent recommendations

Abstract

Osteoarthritis is the most common joint disease in many populations, which is usually manifested in persons over 40 years. This disease has become one of the main causes of disability and quality of life of patients, including young and middle-aged, of great socioeconomic significance and an urgent problem of modern medicine. Today, we have a fairly significant list of symptomatic slow-acting anti-inflammatory drugs, which have not only a symptomatic effect, but also structural-modifying, that is, the effect of slowing the destruction of cartilage tissue. These drugs include chondroitin sulfate, glucosamine sulfate, diacerein, ginger root extract, unformed soy and avocado compounds. That is, the doctor has the opportunity to choose the drug in the treatment of osteoarthritis. For example, with hyperuricemia, diacerein reliably reduces uric acid levels, as well as glucose levels. And preparations which includes chondroitin sulfate and glucosamine can reduce the pain syndrome with lower back pain. Glucosamine sulfate reduces cholesterol levels.