Abstract
Sustained release is a method to reduce therapeutic drugs side effects by preventing the therapeutic concentration of the drug from fluctuating in the body. Sustained release is used to describe a pharmaceutical dosage form formulated to retard the release of therapeutic drug so that it remains in the systemic circulation for prolonged time and its plasma profile is sustained in duration. Sustained release drug delivery system has been formulated in form of tablets to slow down release of drug from tablets. It works on various mechanisms to control the release rate of drugs. Formulation approaches that have been utilized are drug dissolution, drug diffusion, matrix erosion. Present review work deals with the different aspect of the sustained release tablets.
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