Abstract
The carcinoembryonic antigen (CEA) was measured by radioimmunoassay (RIA) in the serum of patients with carcinoma of the ovary (100), cervix (100), and healthy controls (100). Two methods were used in the RIA for the precipitation of the CEA immune complex: (i) double antibody (DA), and (ii) ammonium sulfate (AS). The mean value of the controls was 14.67 ± 4.09 ng CEA/ml of serum using the DA technique. Based on the control's mean value +2 SD, there were 3% positive results in the control group, 16 and 19% positive results in the ovarian and cervical cancer groups, respectively. With the AS technique, all the control values were less than 1.5 ng CEA/ml of serum. This gave 20 and 3% positive results in the ovarian and cervical cancer groups, respectively. Although the assays (DA and AS) are comparable, the results show that only six ovarian and one cervical cancer patient had positive CEA levels, when determined by both the DA and AS techniques.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
