A Comparative Study of Biochemical Indices between Control and Diabetic Patients

Abstract

Introduction: Diabetes is a major risk factor for number of noncommunicable diseases. Novel factors like lipid profiles have contributed as risk factors for coronary artery disease along with abdominal obesity. So a comparative study is done to know the extent of altered lipid metabolism in NIDDM. Methods: Lipid profiles along with blood sugar levels were done to know the effect of dyslipidemia. Available NIDDM patients with history of diabetes without any complication were taken and equal no. of age & sex matched normal healthy control subjects were recruited in the study. Results: TC showed a highly significant more value (P<0.001) in both male & female NIDDM patients when compared to control group. TG showed higher values in male NIDDM patient than control groups but not statistically significant. But female NIDDM patients showed statistically significant when compared to controls. HDL-C level was lower (P<0.05) in both male & female NIDDM patients when compared to control group. LDL-C showed significant higher value (P<0.01) in male NIDDM patients and (P<0.001) in female NIDDM patients when compared to control group . VLDL-C showed statistically significant higher value (P<0.01) in males & (P<0.001) in females NIDDM patients when compared to control group. Interpretation and Conclusions: Lipid profiles like, TC, LDL-C & TG are more in female NIDDM than male NIDDM patients & controls.