Abstract

Objective To compare the effect of Travoprost and Timolol in treating patients with primary open angle glaucoma.Methods Using randomized,parallel group control study and choosing patients with primary open angle glaucoma (POAG),0.004% Travoprost was applied once a day (7:00PM) in 58 patients of the experiment group and 0.5% Timolol (7:00AM&7:00PM) in 30 patients of the control group for 1 year.Intraocular pressure (IOP),visual field and adverse reaction were observed.Results The IOP in the experiment group decreased 8.21±3.44mmHg and the visual field score reduced 0.45±1.10,the reduction in the control group was 5.44±l.78mmHg and the score increased 0.47±1.01.Visual field score of the two groups were stable.Conclusions Comparing with Timolol,Travoprost is more effective and stable in reducing IOP in patients with POAG. Key words: Travoprost; Timolol; Glaucoma

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