Abstract
Objective To study the efficacy and safetv of latanoprost and timolol maleate in treating open angle glaucoma.Methods Open angle glaucoma patients were enrolled and randomly divided into observation group (given latanoprost and timolol maleate) and control group (given timolol maleate).Then RNFL thickness,visual field defect degree were detected and adverse reaction was observed.Results ① Field defect in above view field,lower visual field,visual field,nasal visual field of observation group were lower than those of control group; ② RNFL thickness in above view field,lower visual field,visual field,nasal visual field of observation group were higher than those of control group; ③There were no statistical significant difference found in incidence of adverse reaction cases between two groups.Conclusion Latanoprost and timolol maleate have positive clinical value for it can improve RNFL thickness,visual field defect and achieve equal safety. Key words: Open angle glaucoma; Latanoprost; Timolol maleate; Visual field defect
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