Abstract
BackgroundDesmoplastic ameloblastoma (DA) is a rare variant that accounts for approximately 4–13 % of ameloblastoma, displaying significant differences in anatomical site, imaging, and histologic appearance. It has been included in WHO classification of head and neck tumor (WHO-2005) as a variant of ameloblastoma. The tumor resembles benign fibro-osseous lesion for being frequently occurring in the anterior region of jaws as a mixed radiopaque-radiolucent lesion.Case presentationWe present a case of DA in a 43-year-old female with a painless swelling in the anterior region of mandible. No fluid was evident on fine needle aspiration. A mixed lesion with multilocular appearance was evident on both panoramic radiographs as well as computed tomography scan. An incisional biopsy confirmed it to be a case of desmoplastic ameloblastoma. Segmental mandibulectomy was performed from teeth 35 to 44. The patient is on routine follow-up and is currently free of ailment.ConclusionsThe present case deserves emphasis because of its unfamiliar appearance, potentially aggressive nature and deceptive radiologic appearance maximizing the chances of misdiagnosis. So, the clinician should be alert enough to include desmoplastic ameloblastoma in differential diagnosis of any lesion/growth with mixed radiolucent-radiopaque appearance having ill-defined borders and occurring in anterior maxilla or mandible.
Highlights
Desmoplastic ameloblastoma (DA) is a rare variant that accounts for approximately 4–13 % of ameloblastoma, displaying significant differences in anatomical site, imaging, and histologic appearance
DAs are similar to conventional solid ameloblastomas regarding the age and gender distribution, tumors present a strong proclivity for the anterior region with equal incidences on either of the jaw [8]
Desmoplastic ameloblastoma exhibited desmoplasia of the stromal connective tissue which is thought to be a maturational change in a solid ameloblastoma, as it has been observed that dense collagenisation may be seen in tumors with a long history
Summary
The desmoplastic ameloblastoma is characterized by distinctive clinicoradiographic and histologic features. The horizon of differential diagnosis of Desmoplastic ameloblastoma extends over any mixed radiolucent–radiopaque lesion with inconspicuous radiographic margin presenting in the anterior–premolar region of the maxilla/mandible. Authors’ contributions NSL conceived, and drafted the manuscript. HS and NSL maintained the regular follow-up of the patient, counselling and photographs. All authors participated in the revision of the manuscript. All authors read and approved the final manuscript. Author details 1 Department of Oral and Maxillofacial Surgery, Hospital of Stomatology, Jilin University, Qinghua Road, Changchun 130021, Jilin Province, People’s Republic of China. 3 Department of Oral Pathology, Hospital of Stomatology, Jilin University, Qinghua Road, Changchun 130021, Jilin Province, People’s Republic of China
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