Desmoplastic ameloblastoma in the mandible: A case report

Arushi Pandey,Sandeep Singh Bhatia

doi:10.18231/2393-9834.2018.0038

Abstract

Introduction: 0.9 – 12.1% of all cases of ameloblastoma account to be Desmoplastic Ameloblastoma (DA). The presentation of the tumor is often similar to benign fibro-osseous lesions both clinically as well as radiographically. Histologically, DA is made up of small nests and strands of odontogenic epithelium which seem to be compressed by the highly collagenized stroma. We report a case of DA in a 44-year-old female with a mildly painful swelling in the anterior region of mandible. The lesion had a multilocular appearance on both panoramic radiographs as well as in the computed tomography scan. Histologically, the lesion was confirmed to be a case of DA. Regardless of the fact that DA is a rare entity, its aggressive nature binds the clinician to be cautious enough to include DA in the differential diagnosis of any lesion/growth clinically and radiographically mimicking a benign fibro osseous lesion. Keywords: Ameloblastoma, Desmoplasia, Mandible.

Highlights

The most common classification of ameloblastoma is on the basis of its histological presentation, as being plexiform, follicular, desmoplastic, granular cell type, basal cell type, clear cell type and acanthomatous.[1]
Origin of the lesion: Kishino et al.[11] identified oxytalan fibers in the connective stroma of Desmoplastic Ameloblastoma (DA) with the help of potassium monopersulfate-aldehyde fuchsin stain. He proposed that these fibres which were present in the periodontal membrane could be the source of origin of DA
While others suggested the rests of Malassez present in the periodontal membrane to be the source of origin of DA.[12]

Summary

Introduction

The most common classification of ameloblastoma is on the basis of its histological presentation, as being plexiform, follicular, desmoplastic, granular cell type, basal cell type, clear cell type and acanthomatous.[1] In the year 1984, Eversole documented several cases and gave a detailed description of DA. He coined the term “ameloblastoma with pronounced desmoplasia” for it.[2]. Clinical Presentation: A 44-year-old lady came to our dental hospital with a swelling in the chin area. The patient was referred to higher centres for treatment and follow up

Discussion

Findings

Conclusion