Desmoplastic Ameloblastoma —A Case Report

G Gandhi,A Amirthagani

doi:10.4236/ojst.2017.73013

Abstract

The desmoplastic ameloblastoma (DA) is a rare variant of the conventional ameloblastoma. It accounts for only 4% to 13% of all ameloblastomas. Desmoplastic ameloblastoma (DA) was included in the World Health Organization Classification of Head and Neck Tumors (WHO-2005) as a variant of ameloblastoma with specific clinical, imaging and histological features. The desmoplastic variant of ameloblastoma usually appears in the anterior and premolar regions as a mixed radiolucent and radiopaque lesion, sometimes resembling a benign fibro-osseous lesion [1]. Ameloblastoma is a locally aggressive tumor that may cause recurrence and in rare cases, malignant transformation with repeated postsurgical recurrences [2] [3]. In this paper we present a case of a 47-year-old female with swelling in the left upper jaw, bopsy of which turned out to be desmoplastic ameloblastoma.

Highlights

Until now, only 162 cases have been reported in literature
In this paper we present a case of a 47-year-old female with swelling in the left upper jaw, bopsy of which turned out to be desmoplastic ameloblastoma
The desmoplastic ameloblastoma (DA) was first described by Eversole et al in 1984 as a new type of ameloblastoma with unique histological pattern characterized by the presence of islands of ameloblastic columnar cells surrounding spindle-shaped stellate reticulum like cells in a stroma with marked desmoplasia

Summary

Introduction

Only 162 cases have been reported in literature. The DA was first described by Eversole et al in 1984 as a new type of ameloblastoma with unique histological pattern characterized by the presence of islands of ameloblastic columnar cells surrounding spindle-shaped stellate reticulum like cells in a stroma with marked desmoplasia. The desmoplastic variant of ameloblastoma usually appears in the anterior and premolar regions as a mixed radiolucent and radiopaque lesion, sometimes resembling a benign fibro-osseous lesion. A differential diagnosis between the osteoplastic variant and fibro-osseous lesions such as fibrous dysplasia or ossifying fibroma can be very difficult. Different methods of treatment have been described, but most authors agree that the management of solid ameloblastoma should be radical and primary curative. The conservative therapy, such as enucleation, is associated with high rate of recurrences [5]

Case Report

Findings

Discussion