Abstract
In this paper, we provide a brief overview of fiber optic biosensors for use in MedTech, specifically to aid in the diagnoses and treatment of those with chronic medical conditions. Fiber optic cables as components of biological sensors make them especially effective in biological systems that may require ultra-sensitive detection of low-frequency signals in hard to reach areas. This systematic review focuses on the differentiating factors of fiber-optic biosensors, which are tailored to apply the sensor to specific health needs. The main components of FOBS (fiber optic biosensors) such as biosensing elements, fiber optic cables, optical element enhancements, transducers, sensing strategies, photodetectors, and signal processing are covered in detail by showcasing the recent developments in modifications to these components. This paper pays particular attention to the alterations made in biosensing elements including pH elements, enzymatic elements, as well as those sensors utilizing antibodies and whole-cell bacteria. This paper reviews and discusses several published examples in the research stage of development to give the reader an overall scope of the field. The need for research on biosensing equipment is increasing, as the number of individuals with chronic diseases and the geriatric population require more effective, accurate, and mobile sensing ability and reduced invasiveness. FOBS offer a sensing solution that is accurate, tailorable to almost any clinical need, has abundant and relatively cheap material requirements, and a well-established technological base in fiber optic technology. This small price tag and large market potential make FOBS a desirable research area.
Highlights
According to a report by Global Market Insights, the United States biosensing market will exhibit a 7% increase by 2024, reaching a potential total of $30 billion [1]
A project noted in the journal of coatings technology and research found that coating the optical fiber in glucose oxidase increases the sensing area’s susceptibility to picking up fluorescence signals produced by the organic metal complexes that are quenched by oxygen
The main components of a Fiber optic biosensors (FOBS) discussed in this paper are optical fiber and transducer, biorecognition element, and photodetectors
Summary
According to a report by Global Market Insights, the United States biosensing market will exhibit a 7% increase by 2024, reaching a potential total of $30 billion [1]. A good example evolved to monitor more a more diverse array of diseases, become smaller and increasingly complex This practice is the photodetector (a detector designed to capture data from light photons). This includes mirrors and beam splitters that are used to alter the pathway of the light beam to achieve a more potent signal to be propagated by the fibers in the sensor. Several types of photodetectors can be used in FOBS applications, depending on the signal that is being captured [6]
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