Abstract
Wearable electrochemical sensors represent a point of convergence between lab-on-a-chip technologies, advanced microelectronics and connected intelligence. These three pillars establish data flow from analytes present in body fluids, to the Cloud infrastructures towards next-generation personal healthcare and wellness. The design of electrode-embedded interfacing instrumentation in advanced CMOS technology nodes offer a number of challenges spanning from ultra-low power operation, small footprint, sufficient general purpose operability, and compatibility with advanced CMOS technology nodes. This paper presents a low-power frontend with extended amperometric dynamic range and wide potentiostatic range for electrochemical transducers with Delta-Sigma (ΔΣ) digital output. The second-order single-bit continuous-time ΔΣ modulator architecture reuses the electrochemical cell dynamic characteristics for quantization noise shaping, while the differential potentiostat enables 1.8 V pp of control range under single 1.2-V supply. The proposed frontend has been integrated in TSMC 65-nm CMOS technology occupying 0.07 mm 2 . From electrical and electrochemical tests, the micro potentiostat achieves a Signal-to-Distortion-and-Noise of 80 dB with 15-μW power consumption and a combined multi-scale dynamic range of 105 dB.
Highlights
Commercial wearables offer real-time tracking of physical activity and physiological signals through a complex combinations of GPS, MEMS triaxial accelerometers/gyroscopes and infrared light emitters/detectors [1]
No significant differences in the calibration curve parameters nor linearity are observed between the ASIC prototype and the reference commercial handheld potentiostat
Table 2 compares the performance of the presented potentiostatic M to state-of-the-art CMOS circuit frontends for electrochemical sensors
Summary
Commercial wearables offer real-time tracking of physical activity and physiological signals through a complex combinations of GPS, MEMS triaxial accelerometers/gyroscopes and infrared light emitters/detectors [1]. The integration of chemical sensing along with physical sensing may unfold the true potential of wearable technologies [2]. Tears, interstitial fluid and urine provide unique opportunities to access to a rich set of body analytes [3]. The embodiment of such wearable devices need to deal with conformability, flexibility, durability, data integrity, light weight, and low production cost. For this reason, specific design techniques towards low-cost and low-power CMOS circuit interfaces for electrochemical sensors are experimenting a growing interest [4].
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
