Abstract
Abstract Introduction To identify the status of health-related quality of life (HR-QoL) domains in children with sleep disturbance. Methods Patients ages 5–17 years visiting sleep laboratory from 09/2019 to 01/2020 for overnight PSG participated in the study. Age and sex matched control participants were seen in general pediatrics during 02/2020 for issues other than sleep disturbance. HR-QoL was assessed by PROMIS V1.0 questionnaires. Statistical analysis was conducted using R 3.6.0. Results 122 patients were included in the final analysis: 70 males (57.4%). Ninety nine (81.15%) patients were included from the sleep laboratory and 23 (18.85%) controls were recruited from the department of pediatrics. Among the patients visiting sleep laboratory, thirty one (25.4%) had mild OSA, 12 (9.8%) moderate OSA, 19 (15.6%) severe OSA, 37 (30.3%) were diagnosed with No-OSA. Twenty three (18.9%) controls were visiting to the hospital for their routine wellness examination requiring no PSG. Severity of OSA was not correlated with any HR-QoL domain. Patients visiting the sleep laboratory had lower life satisfaction (p=0.05) and higher physical stress experience (p=0.005). Age, BMI were negatively and N3 sleep was positively associated with family relations (p<0.001, 0.03, 0.006, respectively). N3 sleep was positively and age was negatively associated with life satisfaction (p<0.001, p=0.003, respectively). Increase in arousals was associated with increased physical stress experience (p=0.03). N3 sleep and anger were negatively associated with each other (p=0.05). Conclusion Children visiting sleep laboratory had higher physical stress experience and lower life satisfaction as compared to controls. Deep sleep was associated with problems with family relations, life satisfaction and anger. Regression analysis suggested that age was negatively associated with family relations and life satisfaction. Support (if any) None
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