Abstract
As chronic wounds pose an immense threat to the health of patients and current treatment strategies are unsatisfactory, our study aims to find new possible drug candidates to aid healing of chronic wounds. We screened 141 candidates of an inhibitor-library in our established ex vivo wound healing organ culture (WHOC) model. The effects of these inhibitors were analyzed regarding their influence on wound area, wound perimeter, and wound volume. Area and perimeter were assessed based on two-dimensional reflected light microscopy images.
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