Abstract

Fibromyalgia (FM) is a disorder characterized by chronic widespread musculoskeletal pain often associated with debilitating fatigue, unrefreshing sleep, cognitive complaints, depression, and anxiety. Patients with FM have evidence of centrally maintained or amplified pain. Cognitive and emotional factors also play a significant role in the impact of FM on health. The treating clinician should be able to identify the symptoms of FM and sort through the differential diagnosis, understand its relationship to comorbid rheumatic diseases, assist the patient in distinguishing central pain from mechanical or inflammatory pain, and provide management approaches that address patient symptoms. Management of FM includes use of nonpharmacologic and pharmacologic treatments.

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