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Abstract
The polysaccharides-based systems have been interesting in the biomedical fields for the delivery of therapeutics. Polysaccharides act as promising biomaterials and offer various advantages such as biological safety, easy availability, nontoxicity, biodegradability, and biocompatibility. Polysaccharides can easily be modified by simple/chemical pathway to form novel functional polysaccharides, which have the capability to control the drug release. Further, they can also be combined with other polysaccharides or biomaterials to deliver bioactive molecules. Various polysaccharides are commercially available, among them chitosan (CS) and alginate (Alg) have been extensively investigated in drug targeting and delivery of bioactive molecules. In this chapter, dual CS- and Alg-based therapeutic carriers have been reviewed. The fabrication of therapeutic carriers, morphological characteristics, encapsulation efficiency, release characteristics of entrapped therapeutics, impact on drug’s bioavailability, and their biomedical potentials are included in this chapter.
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