Abstract

This chapter will discuss the application of enzymes to carry out biotransformation reactions for the synthesis of building blocks of new drugs within the fine chemicals industry. It will concentrate on the marine environment to discover novel enzymes that have applications in this important area of substainable chemistry. Marine enzymes that have been cloned and isolated from bacteria, archaea, macro algae and viruses will be used to illustrate specific examples and applications. These enzyme activities include haloperoxidases, dehalogenases, alcohol dehydrogenases, L-aminoacylases, proteases, esterases and lipases. The biochemical and structural studies on these marine enzymes will be described in relation to their mechanism of action and evolutionary diversity with regards to related enzymes.

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