4 - Anilines and Nitrobenzenes

Abstract

This chapter discusses anilines and nitrobenzenes that are processed for use as herbicides and fungicides. These are not pesticides and are biodegradable. The chapter first reveals the processing for 4-Aminobiphenyl and 4, 4’- methylene-bis-(2-chloroaniline), which are carcinogens. 1, 3-Diaminobenzene(m-Phenylenediamine) is also discussed. By the perfused rat liver; 1, 3-diaminobenzene (MPD) is metabolized to three identified N/-acetylated derivatives that are identical to the metabolites excreted in rat urine. 3, 4-dichloroaniline and its treatment is detailed. 2, 6-dichloro-4-nitroaniline (DCNA) that acts as a herbicide and fungicide is briefly reviewed. The treatment of 2, 6-diethylaniline (DEA) involves incubation of 2, 6-Diethylaniline (DEA) with NADPH fortified rat liver microsomal enzymes, which produces 4-amino-3, 5-diethylphenol (ADEP) as the major oxidation product. The next compound 2, 4- and 2, 6-dimethylanilines is produced by rats and dogs. 2, 4-dinitrophenol is a bacterial strain RB1, which is isolated by enrichment cultivation with 2,4-dinitrophenol, degrades this phenol into two aliphatic acids. Dinitrophenol, Dinitrotoluene in two different compositions, Fluoroanilines, Diphenylamine, Nitrophenol, and Pendimethalin are the other compounds that are discussed.