Abstract
Cranberry (Vaccinium macrocarpon) is widely applied for urinary tract health, despite conflicting research. Its efficacy for urinary tract infections (UTIs) is likely due to its ability to inhibit the adhesion of Escherichia coli to genitourinary epithelium. Clinical research indicates that cranberry may be beneficial for gingivitis, dental plaque, dyslipidemia, diabetes, Helicobacter pylori, intestinal dysbiosis, UTI prophylaxis, benign prostatic hyperplasia, rheumatoid arthritis, and prostate cancer. Cranberry juice extracts and constituents exhibit antimicrobial, antiinflammatory, antioxidant, and antiadherence properties. This chapter examines some of the scientific research conducted on cranberry, both alone and in combination formulas, for treating numerous health conditions. It summarizes results from several human studies of cranberry’s use in treating oral and dental, cardiometabolic, gastrointestinal, genitourinary, autoimmune, and oncologic disorders. Finally, the chapter presents a list of cranberry’s Active Constituents, different Commonly Used Preparations and Dosage, and a Section on “Safety and Precaution” that examines side effects, toxicity, and disease and drug interactions.
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