Abstract
Generally tissue samples from histopathology or open biopsy are used for cytogenetic analysis and only few studies have used tissue samples from Fine Needle aspiration for chromosomal analysis. To start neoadjuvant chemotherapy in bone sarcoma patients, we need final diagnosis. Open biopsy has its own disadvantages. FNAC and cytological examination can give valuable information about the tumor. Apart from immunocytochemistry and electron microscopic examination of aspirated tissue, chromosomal analysis has also become a tool in diagnosing bone sarcoma.
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