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Abstract
The biosynthesis of penicillin is strongly repressed by glucose Glucose represses (but does not inhibit) the incorporation of (14C)-valine into penicillin. Non-metabolizable glucose analogues do not exert carbon catabolite regulation. The effect is however exerted by 2-deoxyglucose. Glucose repression of penicillin biosynthesis is not reverted by cyclic-AMP.
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