18259 A 4-week study to determine the safety in use and efficacy of a hydrating body cream and microdermabrasion paste on subjects with dry, rough, and bumpy skin texture

Abstract

Keratosis pilaris (KP) is a common condition that causes dry, rough patches and tiny bumps on the body’s skin. It can’t be cured but the symptoms can be minimized with the use of exfoliants and hydrating agents. A 4-week clinical study was performed to assess efficacy and safety of a hydrating body cream featuring 3-dimensional 3-polymer interpenetrating network (3D3P-IPN) alone or in conjunction with a microdermabrasion paste. The efficacy was measured with clinical grading during live and pictures analysis, hydration with conductance and self-assessment at baseline, and weeks 2 and 4. There was a significant improvement in skin hydration after 2 and 4 weeks in both groups as revealed by both conductance and clinical grading on tactile and visual skin texture. There were no statistical differences between regimens however directionally better results were noticed in microdermabrasion group. The picture comparison study showed gradual improvements in overall healthy-looking skin, radiance, and minor benefits on erythema, and tone evenness at week 2 and 4 evaluations. The subjects scored both regimens as safe and well tolerated with no stinging, burning, nor edema signs. A significant reduction in dryness, itching, roughness, and gradual improvements in softness, radiance, tone evenness, and overall better-looking skin was observed at weeks 2 and 4 compared with baseline. This study demonstrated that a body cream featuring 3D3P-IPN technology alone or with the addition of a microdermabrasion paste effectively replenishes hydration and improves the overall skin condition associated with Keratosis Pilaris.