Abstract

This chapter discusses various factors influencing recovery after an injury or disorder. A variety of factors influence recovery from behavioral deficits after stroke. They may be grouped as injury-specific, individual-specific, and deficit-specific factors. Injury-specific factors include the mechanism of the injury, its size, and its location. Cerebral organization may influence recovery from both aphasia and right-hemisphere deficits. Recovery from behavioral deficits may be influenced by a variety of lesion-specific factors, including size, type, and location. Lesion type also influences recovery. As infarcts destroy brain tissue, recovery may be quite indolent after large ischemic infarcts. A variety of neurophysiological processes may account for the neurological recovery that occurs after brain injury. It has been speculated that recovery occurs because of the regression of diaschisis, the resolution of edema and mass effect, and the establishment of collateral blood supply in instances of ischemic stroke. Some recovery of function must reflect the resolution of temporary accompaniments of acute stroke.

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