Abstract

Polymeric biomaterials have occupied a crucial place in the development of modern medicine. Polyhydroxyalkanoates (PHAs) have been well-known as natural, biodegradable, nontoxic, biocompatible, and renewable thermoplastics since the 20th century. The resourcefulness of PHAs in terms of varying monomer chemistry, desired surface modifications gives rise to polymers with abundant and notable physical and mechanical property diversity. PHAs have been explored as a promising biomaterial for varied biomedical applications viz. sutures, wound dressings, bone and cartilage scaffolds, tissue engineering scaffolds, fabrication of resorbable medical devices such as cardiovascular grafts, drug delivery, and nerve guides, etc. This chapter mainly focuses on various surface modification reactions attempted to develop these polymers as an efficient biotextile.

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