Abstract
This chapter reviews tissue sealants and adhesives used in surgery, which can be categorized as bioresorbable or biostable and synthetic or bio-derived. The fastest growing of these categories commercially is synthetic bioresorbable sealants, which form into solid gel in situ. Key characteristics of mechanical properties, application to tissue, mechanisms of bonding and biocompatibility are discussed. Finally, descriptions of the major commercial surgical sealants and adhesives in each category are described.
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