Abstract
Infection in total knee arthroplasty is one of the most devastating complications of an otherwise highly successful operation. The authors emphasize the importance of risk-factor identification and early management. The treatment is complex, depending on many variables: timing of infection, bacteriology, implant stability, host condition and soft tissue impairment. This is the reason why orthopaedic surgeons, microbiologists and infectious disease physicians should work in a multidisciplinary-team for an optimal treatment that includes different options: antibiotic suppression, debridement, one- or two-stage prosthetic replacement and arthrodesis. Amputation is considered as a salvage procedure in patients with life-threatening sepsis combined with massive soft tissue and bone loss.
Published Version
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