Abstract

This chapter presents a review of the 6/sec spike and wave complex. The pattern of the 6/sec spike and wave complex is a controversial waveform for a number of reasons. Over a 30-year period, 1,550 of 61,467 patients showed the 6SW and 839 were chosen as the experimental group for electroclinical correlations. Control groups included randomly selected patients from the EEG files, subjects with a normal EEG, subjects with only slow-wave abnormalities, and those with only spike abnormalities. In the experimental group, more females and Caucasians were found, consistent with many other studies, and a distinctive age distribution was seen with a peak at 11–15 years. The major symptoms were seizures, neurovegetative symptoms, and psychiatric complaints, significantly different from the control groups, except for seizures among patients with focal spikes. Seizures were primarily generalized, but absence attacks were reported in 11% of those with seizures, consistent with a significantly high incidence of 3/sec spike and wave complexes found in the experimental group. Neurovegetative symptoms included headaches, dizziness, blackouts, and gastrointestinal complaints. Psychiatric 342 EEG and evoked potentials symptoms were reported mainly in the form of behavior disorders.

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