Abstract
A new compound 1 and 19 known ones were isolated from Zingiber officinale Roscoe (Zingiberaceae) rhizomes. The structure of 1 was determined as 3-hydroxy-1-(4′-hydroxy-3′-methoxyphenyl)-octadeca-1,3-dien-5-one (1-dehydro-[14]-gingerdione) based on spectral data. The biological activity of several pure compounds was investigated. It was found that [n]-gingerols possessed the most pronounced inhibitory effect on α-amylase activity and formation of advanced glycation end products (AGEs) under in vitro conditions.
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