Abstract
Tissue engineering aims to develop functional tissue substitutes that can be used for reconstructing damaged tissues or organs. To engineer a tissue construct, cells are generally seeded on biomaterial scaffolds that recapitulate the extracellular matrix (ECM) and microenvironment in order to enhance tissue development. Recently, it has been recognized that biomedical nanomaterials play a central role in tissue engineering as they may better support tissue regeneration. Here, we address various biomedical nanomaterials and their effects on cells and tissues. The considerations needed to create a scaffold material for tissue engineering applications are discussed. We will also review the current progress and future directions for nanomaterials in tissue engineering.
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