1-Azafagomine: A Hydroxyhexahydropyridazine that Potently Inhibits Enzymatic Glycoside Cleavage

Abstract

In the Full Paper by M. Bols et al. in Chem. Eur. J. 1997, 3, 940–947 there is a mistake. 1-Azafagomine (16) was erroneously reported to have a pKa of 3.9. Subsequent pKa measurements[1] have revealed that this is incorrect. The correct pKa value of 16 is 5.3. The difference does not influence the conclusions, however. [1] H. H. Jensen, M. Bols, J. Chem. Soc. Perkin Trans. 1 2001, 905–909.