Abstract
Background Cardiovascular involvement is frequent in chronic obstructive pulmonary disease (COPD), with autonomic dysfunction a recognized feature. However, the dynamics of QT interval, a known marker of autonomic dysfunction, from rest to peak exercise in COPD patients has not yet been investigated. The aim of this study was to examine the changes in QT, heart-rate corrected QT (QTc), PR, QRS and RR intervals from rest to peak exercise in a population of stable COPD outpatients and of healthy controls.
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