Abstract
Objective To explore the relationship between fat-free mass (FFM) and peak exercise performance in chronic obstructive pulmonary disease(COPD) patients. Methods 26 healthy subjects and 62 stable COPD patients performed incremental cardiopulmonary exercise testing with cycle ergometer. 62stable COPD patients were divided three groups(mild COPD,moderate COPD,severe COPD) according to FEV1%pred, peakVO2, peakLoad, peakO2 pulse, AT were measured during exercise. FFM and routine subjects, peakVO2 ,peakVO2 %pred,peakLoad,peakLoad%pred,peakO2 pulse,peakO2 pulse% pred and AT peakLoad%pred,AT and peakO2 pulse% pred ( r =0. 671,0. 478,0. 423,0. 618, P＜0. 05) in COPD patients.Conclusions FFM is significantly associated with muscle aerobic capacity and exercise tolerance in COPD patients. Key words: Fat-free mass; Chronic obstructive pulmonary disease; Cardiopulmonary exercise testing
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