Патогенная роль Moraxella и направления в борьбе с моракселлезной инфекцией

Abstract

Infectious bovine keratoconjunctivitis (IBk) is a common infection of cattle, manifested mainly by eye damage. Although it is not a fatal disease, its economic importance is enormous, as it leads to a decrease in livestock weight gain and a reduction in milk production. The main cause of this disease is a bacterial infection of the genus Moraxella. Environmental factors that contribute to the etiopathogenesis of infectious bovine keratoconjunctivitis (IBK) include facial flies and mechanical irritation from plant spines and dust. The disease can be controlled, and its spread can be reduced by containing the spread of facial flies. The use of traditional methods of treatment, such as the use of antibacterial chemicals, may be ineffective due to the factors of resistance and immunity of these bacteria. The development of a vaccine can be expensive and time-consuming, due to the external localization of the infection, it will be difficult to achieve a protective effect. Therefore, the authors consider it relevant to use new methods to combat moraxella infection with the help of bacteriophages. Knowledge of the genetic and biological structure of phages and their characteristics plays an important role in choosing the right methods of phage therapy and developing new phage prevention strategies. The use of bacteriophages has a promising value in solving the problem of bacterial resistance to antibiotics.