Оценка коэффициента LAF в качестве критерия риска острого приступа закрытоугольной глаукомы

Abstract

Purpose. To study the possibility of using the LAF coefficient in predicting an acute attack of angle-closure glaucoma (AACG) in anatomically short eyes of Europoids. Material and methods. In total, 4 groups of patients were formed: healthy individuals with hyperopia, patients with primary angle closure (PCA) of the anterior chamber, patients with primary angle-closure glaucoma (PACG), and patients with an acute attack of angle-closure glaucoma. The anteroposterior axis of the eye (APA), lens thickness (LT) were studied, and the LAF coefficient was calculated based on the results of these studies. Results. For each of the three factors studied (LT, APA, and LAF), an ROC analysis was performed to identify the cut-off points that best separate the hyperopic and acute attack groups. Cut-off points, sensitivity, specificity, areas under the ROC-curves (AUC) were found. Conclusion. Comparative analysis of LT and LAF parameters in the groups of hypermetropes, patients with PCA and with the initial stage of PACG did not reveal significant differences. In the acute attack group, LT and LAF were statistically significantly higher than the other groups. It was revealed that the LAF coefficient provides a better separation of the group of hypermetropes and the group of acute attack of the primary angle-closure, in comparison with the indicators of LT and especially the APA of the eyes. Our data showed that a high risk of an acute attack of glaucoma in eyes with a short APA occurs at LAF values greater than 2.332. This is confirmed by the high sensitivity, specificity and AUC of this indicator. Keywords: LAF coefficient, acute attack of angle-closure glaucoma, hypermetropia, primary closure of the anterior chamber angle