Abstract
Introduction. The etiology and pathophysiological links of hand-arm vibration syndrome have been sufficiently studied today, but the issue of early diagnosis, prevention and treatment of patients with a comorbid phenotype remains relevant. Aim. Study of nutritional and metabolic status in patients with the comorbid phenotype of hand-arm vibration syndrome in combination with arterial hypertension. Materials and methods. An analysis of nutritional and metabolic parameters was carried out on the basis of the Regional Center for Occupational Pathology in Novosibirsk in 431 people working at the aircraft plant named after V.P. Chkalov, Novosibirsk. Of these: 104 patients diagnosed hand-arm vibration syndrome of the stage I, 101 patients with hand-arm vibration syndrome in combination with arterial hypertension, 107 patients with stage I-II arterial hypertension and 119 people working at the same enterprise without contact with vibration. Results. The analysis revealed a worse nutritional-metabolic situation in the group of a comorbid variant of hand-arm vibration syndrome in combination with arterial hypertension, and also showed the relations between indicators of nutritional status and actual nutrition indicators. Conclusion. As a result of studying nutritional-metabolic status of the multifactorial model of hand-arm vibration syndrome in combination with arterial hypertension, the most informative integral data are presented that determine the disorders in the studied phenotype. The acquired knowledge can be aimed at optimizing early diagnosis and prevention, as well as predicting nutritional and metabolic disorders in hand-arm vibration syndrome in combination with arterial hypertension.
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