ИСПОЛЬЗОВАНИЕ ВИТАМИННО-МИНЕРАЛЬНОГО КОМПЛЕКСА В КОМБИНИРОВАННОЙ ТЕРАПИИ ПАЦИЕНТОВ С ОЖИРЕНИЕМ И САХАРНЫМ ДИАБЕТОМ 2-ГО ТИПА: РАНДОМИЗИРОВАННОЕ, КОНТРОЛИРУЕМОЕ КЛИНИЧЕСКОЕ ИССЛЕДОВАНИЕ

Abstract

Low caloric diet is used in the complex treatment of patients with diabetes mellitus and obesity. However, the reduced caloric food can inadvertently lead to decreased intake of micronutrients. The main goal of the research was to assess the necessity and effectiveness of the vitamin-mineral complex in the treatment of type 2 diabetes with obesity. Methods: 80 females suffering from type 2 diabetes and obesity, ranging from 40 to 65 years old participated in the study. The total patients were divided into two groups, each containing 40 patients. All patients were given a personalized diet and 1000mg of metformin every day. The experimental group, besides that, received vitamin-mineral complex. The biochemical analysis of the blood, composition of the body, and the complaint on micronutrient deficiency were taken before the experiment and after 14 days of the therapy. Results: Supplementation of the vitamin-mineral complex was associated with higher blood serum levels of vitamins B6, B12, B9, C, D, potassium, calcium, magnesium and zinc, and lower levels of glucose. Clinical manifestations, associated with micronutrient deficiency, were significantly decreased in patients who were given vitamin-mineral complex. All these changes were valid both in relation to the initial level in the study group and to the indicators after treatment in the control group. Conclusion: Micronutrient supplements may be a very important part of the combined therapy of patients with diabetes mellitus and obesity.