Abstract
Langerhans cell histiocytosis (LCH) is a pathology rarely encountered in clinical practice. This disease has a multifaceted clinical picture, multiorgan damage, a varied course and presents significant diagnostic difficulties due to the lack of generally accepted international algorithms. In the early stages of the disease, patients turn to pediatricians, traumatologists or dermatologists, which leads to frequent diagnostic errors and inadequate therapy. Doctors of various specialties should pay attention to patients with soft tissue swellings, recurrent otitis and dermatitis in the absence of effect from the therapy and promptly refer them to an oncologist. The article presents an analysis of cases of Langerhans cell histiocytosis in children of the Oncohematology Department of the Children’s Republican Clinical Hospital in Kazan over a ten-year period, indicating the characteristic initial features of the disease for early diagnosis at the outpatient stage.
Published Version
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