Сравнение ранних анатомических и морфофункциональных результатов различных методик закрытия сквозных макулярных разрывов большого диаметра

Abstract

Relevance. Full-thickness macular hole (FTMH) is a vitreomacular interface pathology leading to a significant visual acuity decrease. Traditional surgery of FTMH is not effective enough. With the constant improvement of FTMH surgery, a comparative analysis of various surgical techniques is relevant. Purpose. To compare the early anatomical and functional results of large-diameter FTMH surgery using platelet-rich plasma (PRP) and the technique of hole edges convergence with the intraoperative optical coherence tomography (OCT) control. Material and methods. A randomized study was conducted on two comparable groups of patients. In both groups, surgical treatment of FTMH was performed, the difference was in the direct closure of the FTMH: PRP was used in the first group, the closure of MH was performed with intraoperative OCT control according to the proposed method in the second group. Results. The methods of FTMH closing were comparable in safety. Functional and anatomical results were comparable and did not differ significantly. A difference in the outer retinal layers matching was noted by OCT 1 week after surgery. In group 2, there was a greater number of FTMH closures with the formation of a U-shaped profile of the foveolar zone, which was accompanied by a better inner and outer retinal layers matching. Conclusion. The studied methods of FTMH treatment are comparable in functional results. However, it is necessary to continue studying and analyzing the long-term data. Keywords: macular hole, vitreoretinal surgery, platelet-rich plasma, optical coherence tomography